FIG. 3.

Mean (±SEM) frequencies of CD4⁺ IFN-γ⁺ RV-specific T cells in the five subject populations: symptomatic RV-infected adults (n = 8), RV-exposed laboratory workers (n = 5), asymptomatic RV-infected adults (n = 4), healthy nonexposed adults (n = 7), and symptomatic RV-infected children (n = 12). For the adults and children with diarrhea for whom we had more than one sample, the means were calculated using the sample with the highest response (Tables 2 and 3). We excluded from the calculation of symptomatic adults subjects A09 and A10, who were only studied 32 and 42 DAOD (Table 2). *, statistically significant differences between the responses of children and healthy adults (P < 0.01; Mann-Whitney); #, statistically significant differences with the response of children (P < 0.01; Mann-Whitney).