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. 2026 Sep 25. Online ahead of print. doi: 10.1039/d6ra07055h

Table 8. Dipole moment in the gas phase (µg) and in ethanol solvent (µs), solvation free energy (ΔGsolv), and partition coefficient (log P) of investigated molecules.

Molecules µ g (D) µ s (D) Δµ (D) ΔGsolv (kcal mol−1) log P
REF 2.45 3.12 0.67 −12.30 3.85
M1 4.82 6.94 2.12 −18.20 4.65
M2 5.63 8.41 2.78 −19.45 4.92
M3 5.41 8.12 2.71 −19.10 4.88
M4 5.85 8.93 3.08 −19.80 5.01
M5 6.21 9.54 3.33 −20.15 5.18
M6 7.03 10.87 3.84 −21.05 5.42