TABLE 1.

Induction of luciferase in the presence of TSA^a

Mutant	Fold induction (mean ± SD)
pLTR-WT	11.3 ± 6.1
pLTR-Ebox3x	4.5 ± 2.9
pLTR-IRF	7.2 ± 2.3
pLTR-GRE	4.9 ± 2.8
pLTR-NF1	4.0 ± 0.7
pLTR-NF2	9.4 ± 3.7
pLTR-CRE3x	14.5 ± 8.8
pLTR-Δ21-bp	4.2 ± 2.7

^aStable cell lines harboring the mutant reporters were established. Cells were cultured for 48 h in the presence or absence of TSA, and luciferase activities were determined at 20 h of induction. The levels of induction (i.e., ratio of luciferase units obtained in the presence of TSA versus that obtained in untreated controls) are indicated. The average values from three independent experiments are presented.