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. 2002 May;76(10):5131–5139. doi: 10.1128/JVI.76.10.5131-5139.2002

FIG. 1.

FIG. 1.

Effect of huTNFR:Fc treatment on FDC status in spleens of uninfected mice. Tissues were taken on the indicated days postinjection (d.p.i.) with hu-Ig (control) or huTNFR:Fc, and adjacent frozen sections were stained with FDC-M2 monoclonal antiserum to detect FDCs (upper row; red) or with 8C12 monoclonal antiserum to detect CD35 (middle row; red). PrP was detected on paraffin-embedded sections with the PrP-specific polyclonal antiserum 1B3 (bottom row; red). Expression of FDC-M2, CD35, and PrP in the spleen was undetectable 7 days after treatment with huTNFR:Fc. Original magnification, ×400.