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. 2026 Sep 14;13:1945596. doi: 10.3389/fmolb.2026.1945596

TABLE 2.

Cox regression analysis using PFI as a prognostic category.

Characteristics Total(N) Univariate analysis Multivariate analysis
Hazard ratio (95% CI) P value Hazard ratio (95% CI) P value
TRIM2 501
Low 250 Reference Reference
High 251 0.620 (0.409–0.940) 0.024 0.603 (0.364–0.999) 0.0496
Pathologic T stage 494
T2 189 Reference Reference
T3&T4 305 3.745 (2.118–6.623) 5.64e-06 1.775 (0.840–3.749) 0.1326
Clinical T stage 407
T1&T2 352 Reference Reference
T3&T4 55 3.799 (2.357–6.123) 4.27e-08 1.995 (1.157–3.438) 0.0129
Pathologic N stage 428
N0 348 Reference Reference
N1 80 1.901 (1.175–3.078) 0.0089 1.227 (0.698–2.156) 0.4766
Clinical M stage 460
M0 457 Reference
M1 3 3.587 (0.497–25.906) 0.2055
Gleason score 501
6 46 Reference Reference
7 248 4.362 (0.590–32.245) 0.149 18,097,592.9195 (0.000 - inf) 0.996
8and9and10 207 17.934 (2.490–129.154) 0.0042 49128701.1623 (0.000 - inf) 0.996
PSA (ng/mL) 444
<4 417 Reference Reference
≥ 4 27 4.223 (2.108–8.459) 4.82e-05 2.530 (1.097–5.837) 0.0295
Age 501
≤ 60 225 Reference
>60 276 1.304 (0.865–1.967) 0.205

Bolded values indicate statistical significance.