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. 2026 Sep 14;16:1854567. doi: 10.3389/fonc.2026.1854567

Table 5.

Three-year overall and melanoma specific healthcare costs stratified by stage and presence of prevalent tumors.

Average daily cost alive patient Average cost over 3 years after diagnosis
Dataset Without prevalent tumors With prevalent tumors TOTAL p-value a Without prevalent tumors With prevalent tumors TOTAL p-value a
All patients (n=2978) Overall 17.09 32.25 17.73 <0.001 17,471.23 30,698.34 18,066.41 <0.001
CM-specific 12.83 20.52 13.15 <0.001 13,114.31 19,535.68 13,403.25 <0.001
Stage I (n=2080) Overall 8.07 24.22 8.7 <0.001 8,698.08 25,161.31 9,362.94 <0.001
CM-specific 4.84 13.09 5.16 <0.001 5,217.69 13,603.72 5,556.36 <0.001
Stage II (n=396) Overall 24.4 36.82 25.08 0.013 24,676.67 33,376.11 25,203.91 0.058
CM-specific 18.85 23.28 19.1 0.239 19,065.74 21,107.9 19,189.51 0.538
Stage III (n=267) Overall 65.67 67.57 65.78 0.667 64,719.4 64,751.67 64,721.33 0.674
CM-specific 57.77 57.46 57.75 0.756 56,937.99 55,062.84 56,825.63 0.995
Stage IV (n=126) Overall 104.01 66.18 102.81 0.643 42,819.87 15,231.01 41,287.15 0.181
CM-specific 83.41 24.67 81.54 0.038 34,336.56 5,678.16 32,744.43 0.060
Missing (n=109) Overall 21.94 35.71 22.2 0.985 17,046.81 18,785.66 17,094.67 0.912
CM-specific 17.15 30.24 17.4 0.760 13,326.63 15,908.54 13,397.69 0.760

aKruskal–Wallis test. CM, cutaneous melanoma.