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. 2026 Sep 14;16:1854567. doi: 10.3389/fonc.2026.1854567

Table 6.

Tobit multivariate regression analysis: average three-year costs from diagnosis (dependent variable).

Variable Overall costs Melanoma-specific costs
Estimate a [95% CI] p-value Estimate a [95% CI] p-value
Prevalent tumors
 No ref – ref –
 Yes 9.25 [4.92, 13.58] <0.001 3.90 [0.22, 7.59] 0.038
Sex
 F ref – ref –
 M 1.40 [-0.44, 3.24] 0.137 0.52 [-1.05, 2.09] 0.515
Age
 <45 ref – ref –
 45-54 -0.20 [-3.41, 3.00] 0.901 0.33 [-2.40, 3.06] 0.813
 55-64 0.12 [-3.04, 3.28] 0.940 -0.07 [-2.76, 2.62] 0.960
 65-74 5.59 [2.43, 8.74] <0.001 2.80 [0.12, 5.49] 0.041
 75-84 5.31 [2.01, 8.60] 0.002 0.19 [-2.62, 3.00] 0.896
 >84 -2.85 [-7.59, 1.89] 0.238 -6.09 [-10.13, -2.06] 0.003
Stage
 I ref – ref –
 II 14.91 [12.23, 17.59] <0.001 13.96 [11.68, 16.24] <0.001
 III 54.58 [51.45, 57.70] <0.001 51.06 [48.40, 53.71] <0.001
 IV 30.89 [26.45, 35.33] <0.001 27.47 [23.69, 31.26] <0.001

aExpressed in thousands of euros (€000).