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. 2026 Sep 14;17:1915157. doi: 10.3389/fimmu.2026.1915157

Table 4.

Time-dependent area under the receiver operating characteristic curve (AUC) for predicting renal survival at 36 and 60 months, with 95% bootstrap confidence intervals.

Model 36-month AUC (95% CI) 60-month AUC (95% CI)
CAI 0.70 (0.61–0.79) 0.69 (0.61–0.76)
MEST 0.75 (0.65–0.87) 0.77 (0.67–0.87)
CAI + MEST 0.79 (0.72–0.89) 0.79 (0.73–0.88)
Δ (CAI+MEST − MEST) 0.04 (-0.02–0.12) 0.02 (-0.03–0.10)

AUC values were estimated using the Kaplan–Meier method. 95% confidence intervals (CIs) were derived from 1,000 bootstrap resamples with the percentile method. Δ denotes the absolute change in AUC when CAI is added to the MEST model. The composite renal outcome was defined as doubling of serum creatinine or end-stage kidney disease.Abbreviations: CAI, complement activation index; MEST, Oxford classification; eGFR, estimated glomerular filtration rate.