Table 4.
Time-dependent area under the receiver operating characteristic curve (AUC) for predicting renal survival at 36 and 60 months, with 95% bootstrap confidence intervals.
| Model | 36-month AUC (95% CI) | 60-month AUC (95% CI) |
|---|---|---|
| CAI | 0.70 (0.61–0.79) | 0.69 (0.61–0.76) |
| MEST | 0.75 (0.65–0.87) | 0.77 (0.67–0.87) |
| CAI + MEST | 0.79 (0.72–0.89) | 0.79 (0.73–0.88) |
| Δ (CAI+MEST − MEST) | 0.04 (-0.02–0.12) | 0.02 (-0.03–0.10) |
AUC values were estimated using the Kaplan–Meier method. 95% confidence intervals (CIs) were derived from 1,000 bootstrap resamples with the percentile method. Δ denotes the absolute change in AUC when CAI is added to the MEST model. The composite renal outcome was defined as doubling of serum creatinine or end-stage kidney disease.Abbreviations: CAI, complement activation index; MEST, Oxford classification; eGFR, estimated glomerular filtration rate.