FIG. 1.

Inhibition by heparin of infectivity of Jn and passaged viruses. Jn virus, SW13 cell-passaged viruses (Js1, Js2, and Js5), and Vero cell-passaged virus (Jv1) were incubated with heparin (200 μg/ml) for 15 min prior to their addition to Vero (open bars) and SW13 (gray bars) cell monolayers. Error bars show the standard deviation values calculated for each set of duplicates. The percent inhibition of plaque formation by heparin was calculated as follows: [(1 − plaque number in the presence of heparin)/plaque number for mock-treated control] × 100%.