Table 2.
Association of adverse childhood experiences with accelerated aging
| Exposure | Model 1 | Model 2 | Model 3 | |||
|---|---|---|---|---|---|---|
| OR (95% CI) | P value | OR (95% CI) | P value | OR (95% CI) | P value | |
| Adverse childhood experiences (ACEs) | 1.05 (1.02, 1.08) | 0.003 | 1.04 (1.01, 1.08) | 0.01 | 1.05 (1.01, 1.08) | 0.01 |
| ACEs (Frequency, Percentage) | ||||||
| 0 (1081, 13.0%) | Reference | Reference | Reference | |||
| 1 (2089, 25.1%) | 1.01 (0.87, 1.18) | 0.86 | 1.00 (0.86, 1.16) | 0.98 | 1.00 (0.85, 1.18) | 0.97 |
| 2 (2342, 28.1%) | 1.11 (0.96, 1.28) | 0.17 | 1.10 (0.95, 1.28) | 0.21 | 1.09 (0.92, 1.27) | 0.32 |
| 3 (1458, 17.5%) | 1.15 (0.98, 1.35) | 0.08 | 1.12 (0.95, 1.32) | 0.19 | 1.14 (0.96, 1.36) | 0.14 |
| ≥ 4 (1357, 16.3%) | 1.21 (1.03, 1.43) | 0.02 | 1.20 (1.02, 1.42) | 0.03 | 1.20 (1.01, 1.44) | 0.04 |
| P for trend | 0.002 | 0.01 | 0.01 | |||
Model 1 was adjusted for no covariates.
Model 2 was adjusted for age, sex, ethnicity, marital status, educational level, place of residence.
Model 3 was adjusted for covariates in Model 2 plus BMI status, smoking, alcohol consumption, sleep duration at night, sleep duration at noon, hypertension, diabetes mellitus, cancer, cardiovascular disease.