Skip to main content
. 2002 Jun;76(12):5882–5892. doi: 10.1128/JVI.76.12.5882-5892.2002

FIG. 1.

FIG. 1.

Strategy for the generation of somatic cell hybrids. MDBK cells support the replication of wt BAV3 and wt HAV5 but do not complement viruses with E1 deleted, whereas 293 cells that constitutively express HAV5 E1 proteins support the growth of HAV5 with E1 deleted and the wt. Some of the unique characteristics of both of the parental cell lines (MDBK and 293) could be combined by generating BHH cell lines. Some of the BHH clones should assist the replication of both HAV5 and/or BAV3 with E1 deleted and the wt.