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. 2002 Jun;76(12):5925–5936. doi: 10.1128/JVI.76.12.5925-5936.2002

TABLE 2.

HIV-1 p24 and CMV antigen-specific CD4+ T-cell expansions from HIV-1-infected donors

Donor Peripheral CD4+ T-cell count (cells/mm3) Copies of HIV-1 RNA/ml of plasma HIV-1 p24 stimulation
CMV stimulation
% IFN-γ+ CD4+ T cells at daya:
Expansionb Copies of HIV-1 RNAc % IFN-γ+ CD4+ T cells at day:
Expansion Copies of HIV-1 RNA
0 8 0 8
UH32 826 32,681 0.02 0 0 5,724 0.09 2.2 24.4 39,404
UH90 48 153,713 0.1 0 0 3,314 NDd 0 0 3,154
UH91 107 4,993 0.07 0 0 1,380 0.49 12.08 24.6 <200
UH20 1,273 <20 0.04 4.53 113 8,576 3.75 7.44 1.9 <200
UH8 523 <20 0.04 4.08 102 ND 0.1 0 0 ND
UH52 667 <20 0.03 3.80 100 502 0.66 13.31 20.1 200-400
UH64 942 <20 0.04 0.67 16.7 2,429 0.16 0.35 2.1 <200
a

Percentage of CD4+ T cells that produce IFN-γ in fresh PBMC (day 0) and in culture (day 8).

b

Percentage of IFN-γ+ CD4+ T cells in the culture divided by the percentage in the fresh PBMC.

c

Copies of HIV-1 RNA/ml of culture supernatant.

d

ND, not determined.