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. 2002 Jun;76(12):6356–6363. doi: 10.1128/JVI.76.12.6356-6363.2002

TABLE 2.

Characteristics of ducks treated with lamivudine and 2-amino-6-methoxypurine-2′,3′-dideoxyriboside for 155 days

Duck Sex Mode of infection Initial serum virus level (109 vge/ml) cccDNA pool half-life (days) r2b ASTa (IU/liter)
50 Male In ovo 0.2 38c 0.85 10
65 Male In ovo 4.8 47c 0.96 55
68 Male In ovo 0.6 57 0.94 5
992 Male Congenital 2.7 35 0.97 14
998 Female Congenital 1.1 48 0.98 7
a

Serum AST activity level on day 152.

b

r2, coefficient of determination of exponential regression analysis.

c

Over the first 80 days of treatment before cccDNA levels stabilized in these animals.

HHS Vulnerability Disclosure