TABLE 2.
Characteristics of ducks treated with lamivudine and 2-amino-6-methoxypurine-2′,3′-dideoxyriboside for 155 days
Duck | Sex | Mode of infection | Initial serum virus level (109 vge/ml) | cccDNA pool half-life (days) | r2b | ASTa (IU/liter) |
---|---|---|---|---|---|---|
50 | Male | In ovo | 0.2 | 38c | 0.85 | 10 |
65 | Male | In ovo | 4.8 | 47c | 0.96 | 55 |
68 | Male | In ovo | 0.6 | 57 | 0.94 | 5 |
992 | Male | Congenital | 2.7 | 35 | 0.97 | 14 |
998 | Female | Congenital | 1.1 | 48 | 0.98 | 7 |
Serum AST activity level on day 152.
r2, coefficient of determination of exponential regression analysis.
Over the first 80 days of treatment before cccDNA levels stabilized in these animals.