Table 6.
Multivariable logistic regression analysis.
| Variable | β | SE | Wald | P value | OR | 95% CI for OR |
|---|---|---|---|---|---|---|
| Age (per 1-yr increase) | 0.058 | 0.028 | 4.33 | .037 | 1.06 | 1.00–1.12 |
| Male sex (male vs female) | −0.511 | 0.450 | 1.29 | .256 | 0.60 | 0.25–1.45 |
| Baseline NIHSS (per 1-point increase) | 0.131 | 0.060 | 4.77 | .029 | 1.14 | 1.01–1.28 |
| Baseline SBP (per 10-mm Hg increase) | 0.247 | 0.120 | 4.23 | .040 | 1.28 | 1.01–1.62 |
| ASPECTS (per 1-point increase) | −0.342 | 0.160 | 4.58 | .032 | 0.71 | 0.52–0.97 |
| Atrial fibrillation (yes vs no) | 1.065 | 0.550 | 3.75 | .053 | 2.90 | 0.99–8.52 |
| Pre-stroke antiplatelet use (yes vs no) | 0.668 | 0.500 | 1.78 | .182 | 1.95 | 0.73–5.20 |
| WBC (per 1 × 109/L increase) | 0.113 | 0.080 | 2.01 | .157 | 1.12 | 0.96–1.31 |
| Neutrophils (per 1 × 109/L increase) | 0.039 | 0.090 | 0.19 | .663 | 1.04 | 0.87–1.24 |
| Lymphocytes (per 1 × 109/L increase) | −0.545 | 0.380 | 2.05 | .152 | 0.58 | 0.28–1.22 |
| Hemoglobin (per 1 g/L increase) | −0.020 | 0.015 | 1.81 | .178 | 0.98 | 0.95–1.01 |
| INR (per 0.1-unit increase) | 0.166 | 0.070 | 5.59 | .018 | 1.18 | 1.03–1.35 |
| Fibrinogen (per 1 g/L increase) | −0.223 | 0.200 | 1.24 | .265 | 0.80 | 0.54–1.18 |
| D-dimer (per 1 mg/L FEU increase) | 0.470 | 0.180 | 6.82 | .009 | 1.60 | 1.12–2.28 |
ASPECTS = Alberta Stroke Program Early CT Score, CI = confidence interval, FEU = fibrinogen-equivalent units, INR = international normalized ratio, NIHSS = National Institutes of Health Stroke Scale, OR = odds ratio, SBP = systolic blood pressure, SE = standard error, WBC = white blood cell count, Wald = Wald χ² statistic, β = regression coefficient.