Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2026 Sep 16;10:292. doi: 10.1038/s41538-026-01162-2

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

© The Author(s) 2026

Open Access This article is licensed under a Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License, which permits any non-commercial use, sharing, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if you modified the licensed material. You do not have permission under this licence to share adapted material derived from this article or parts of it. The images or other third party material in this article are included in the article’s Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by-nc-nd/4.0/.

PMC Copyright notice

Fig. 2 — A Schematic diagram of mouse model design and treatment. B, C Evaluation of sperm morphology and sperm quality (sperm counts, sperm motility, sperm viability, sperm malformation rate) in mice, the red arrow indicates sperm malformations (n = 5; Sperm malformations included macrocephaly, microcephaly, headlessness, double heads, irregular head shape, neck/midpiece folding, tail coiling, double tails, etc.). D, E Representative images of H&E staining in testicular and epididymal tissue (caput epididymis, corpus epididymis, cauda epididymis) (scale bars = 50 μm and/or 100 μm; Black triangle, cells shed into the lumen; Blue triangle, loss and disordered cell arrangement). F Statistical analysis of testicular tissue (outer diameter of seminiferous tubule, inner diameter of seminiferous tubule, thickness of seminiferous tubules, n = 5). Note: Control: Control group; As: Arsenic trioxide group; Ribo: riboflavin group; As + Ribo: co-administration of arsenic trioxide and riboflavin group. ***P < 0.001, **P < 0.01 and *P < 0.05 vs. Control group; ^###P < 0.001, ^##P < 0.01 and ^#P < 0.05 vs. As group.