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. 2026 Sep 16;10:292. doi: 10.1038/s41538-026-01162-2

Fig. 4. Effect of riboflavin on key indicators of arsenic-induced Sertoli cell proliferation.

Fig. 4

A–C The mRNA expression level of Wt1, Ar and Gdnf in testicular tissue (n = 5). D, E Immunohistochemistry staining and statistical analysis of SOX9 protein in testicular tissue (Scale bars = 50 μm and 100 μm, n = 5) F Western blotting analysis of the protein expression of SOX9 (n = 3). Note: Control: Control group; As: Arsenic trioxide group; Ribo: riboflavin group; As + Ribo: co-administration of arsenic trioxide and riboflavin group. ***P < 0.001, **P < 0.01 and *P < 0.05 vs. Control group; ###P < 0.001, ##P < 0.01 and #P < 0.05 vs. As group.