TABLE 3.

HCV-derived HLA-A1-, -A2-, -A3-, -B7-, and Patr-restricted peptides for analysis of chimpanzee T-cell responses

Peptide	Protein	Amino acid position	Amino acid sequence	HLA or Patr restriction	Source or reference
6	Core	126	TLCGFADLMGY	HLA-A1	New epitope
7	NS3	1128	CTCGSSDLY	HLA-A1	New epitope
8	NS3	1305	LADGGCSGGAY	HLA-A1	New epitope
9	NS5A	2180	LTDPSHITA	HLA-A1	New epitope
10	NS5B	2922	LSAFSLHSY	HLA-A1	New epitope
11	Core	35	YLLPRRGPRL	HLA-A2	4, 6, 8, 39, 49
12	Core	131	ADLMGYIPLV	HLA-A2	6, 8, 39
13	Core	167	GNLPGCSFSI	HLA-A2	44
14	NS3	1073	CVNGVCWTV	HLA-A2	6, 8, 32, 39, 49
15	NS3	1406	KLVALGINAV	HLA-A2	6, 8, 39, 49
16	NS4B	1807	LLFNILGGWV	HLA-A2	4, 6, 8, 39, 49
17	NS5B	2727	GLQDCTMLV	HLA-A2	4, 6, 8, 39, 49
18	NS1	632	RMYVGGVEHR	HLA-A3	7
19	NS3	1396	LIFCHSKKK	HLA-A3	7
20	NS3	1632	VTLTHPITK	HLA-A3	New epitope
21	NS4B	1863	GVAGALVAFK	HLA-A3	7
22	NS4B	1864	VAGALVAFK	HLA-A3	7
23	Core	41	GPRLGVRAT	HLA-B7	28
24	Core	111	DPRRRSRNL	HLA-B7	12
25	E1	234	NASRCWVAM	HLA-B35a	28
26	NS3	1379	IPFYGKAI	HLA-B7	New epitope
27	E2	651	RCDLEDRDRSELSPL	Patr-A0601	10
28	P7	781	RWVPGAVYAFYb	Patr-A0601	10
29	NS5A	2055	MWSGTFPINAY	Patr-A06	10
30	NS3	1444	FTGDFDSVIc	Patr-B01	27
31	E1	542	TRPPLGNWF	Patr-B13	27
32	NS3	1357	VPHPNIEEV	Patr-B13	27

^aHLA-B35 belongs to the HLA-B7 supertype family.

^bPublished as KWVPGAVYTKY. In this study, the sequence was changed to match the sequence of the infecting virus.

^cPublished as YTGDFDSVI. In this study, the sequence was changed to match the sequence of the infecting virus.