Kinetic analysis of circulating leukocytes (A) and blood differential counts (B and C) following H5N1 infection. Two to three mice were infected i.n. with 106.0 EID50 of DK/Anyang/AVL-1/01 (▴), CK/HK/317.5/01 (○), or CK/HK/220/97 (•) or were mock infected (□). Total white blood cell counts were determined by microscopic counting of leukocytes in heparinized whole blood samples diluted with Turks solution. Blood smears were stained with Hema-3 differential stain, and the percentages of monocytes, polymorphonuclear neutrophils (PMNs), and lymphocytes in CK/HK/220/97-infected (B) and DK/Anyang/AVL-1/01-infected (C) mice were determined.