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Virus levels in SIVmac251-infected infant macaques receiving 3TC or (−)-FTC treatment. All newborn macaques were inoculated at birth orally with SIVmac251. The dashed lines represent 14 untreated SIVmac251-infected infant macaques from a number of previous studies. Four animals were started on 3TC or FTC treatment at 3 weeks of age (arrow). Plasma RNA levels were measured by branched-DNA assay.
