TABLE 1.

Frequent IM-HR during HSV-mediated amplicon replication

Expta	No. of Ampr blue colonies	No. of Kanr blue colonies	% IM-HR
1	448	2,002	22.4
2	654	1,260	51.9
3	56	151	37.1
4	924	2,114	43.7
Control 1	0	1,184b	<0.1
Control 2	0	958	<0.1

^aControl 1, no HSV infection after plasmid transfection. Control 2, pW7 and pW2-lacZ were transfected separately, and the cells were infected with HSV before the DNA was mixed for digestion and ligation.

^bValues were from experiment 1, and no blue colonies were detected in ampicillin plates from the controls in the other three experiments.