Figure 2. Positive correlation between chemically-paired radioisotopes [^64/67Cu]-FAP2287.

(a) Representative coronal images of [⁶⁴Cu]-FAP2287 PET 4h p.i. and [⁶⁷Cu]-FAP2287 SPECT 4, 24 and 48h p.i. showing quantifiable radiotracer uptake and increased retention in the tumor region highlighted by the white dotted circle. (b) Graphical representation of thresholding of mice into higher and lower [⁶⁴Cu]-FAP2287 SUV_Mean (c) Graphical representation showing significant differences in [⁶⁷Cu]-FAP2287 SUV_Mean (4h p.i.) between groups of low and high [⁶⁴Cu]-FAP2287 SUV_Mean