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. Author manuscript; available in PMC: 2026 Sep 30.
Published in final edited form as: Nature. 1999 Aug 26;400(6747):886–891. doi: 10.1038/23730

Figure 2.

Figure 2

Resistance of Bid−/− mice to anti-Fas-antibody-induced mortality and hepatic injury. a, Survival curve of wild-type (WT; filled circles, n = 8) and Bid−/− mice (circles, n = 11) in response to a single i.v. injection of 0.25 μg g−1 anti-/Fas antibody (Jo-2). This represents the survival curve of the best-matched cohort from a total of 24 WT and 40 Bid−/− mice that were injected with anti-Fas antibody. b, c, Haematoxylin–eosin staining of paraffin-embedded liver sections of WT (b) and Bid−/− mouse (c) 2 h after anti-Fas antibody injection. Note the condensed and fragmented nuclei and the haemorrhage in the WT liver. Scale bar, 25 μm.