Table 1.
Comparison of dosimetric parameters between left-sided and right-sided breast cancer patients.
| Parameter | Left-sided (n=54) | Right-sided (n=37) | P value |
|---|---|---|---|
| Whole Heart | |||
| MHD(Gy) | 7.78 (6.80, 9.20) | 5.17 (4.52, 5.79) | <0.001 |
| Heart Dmax (Gy) | 52.64 (49.88, 54.60) | 29.33 (19.80, 35.74) | <0.001 |
| Heart V5 (%) | 37.07 (31.65, 44.58) | 37.67 (29.02, 41.59) | 0.39 |
| Heart V10 (%) | 19.61 (14.36, 23.23) | 11.11 (7.10, 16.75) | <0.001 |
| Heart V20 (%) | 10.69 (8.15, 13.85) | 0.61 (0.00, 2.49) | <0.001 |
| Heart V30 (%) | 5.84 (3.99, 7.66) | 0.00 (0.00, 0.07) | <0.001 |
| Sinoatrial node (SAN) | |||
| SAN Dmean (Gy) | 3.13 (2.47, 4.31) | 8.22 (6.69, 12.70) | <0.001 |
| SAN Dmax (Gy) | 4.85 (3.80, 6.02) | 13.16 (10.40, 19.17) | <0.001 |
| SAN V5 (%) | 0.00 (0.00, 12.67) | 100.00 (82.49, 100.00) | <0.001 |
| SAN V10 (%) | 0.00 | 13.42 (0.48, 85.84) | -† |
| Atrioventricular node (AVN) | |||
| AVN Dmean (Gy) | 2.92 (2.33, 4.35) | 4.08 (2.50, 4.95) | 0.075 |
| AVN Dmax (Gy) | 4.30 (3.16, 6.46) | 6.51 (4.16, 8.55) | 0.009 |
| AVN V5 (%) | 0.00 (0.00, 12.24) | 19.27 (0.00, 42.66) | 0.012 |
| Left ventricle (LV) | |||
| LV Dmean (Gy) | 9.49 (7.42, 10.57) | 2.15 (1.75, 2.73) | <0.001 |
| LV Dmax (Gy) | 50.39 (46.50, 53.19) | 7.48 (5.82, 10.29) | <0.001 |
| LV V5 (%) | 37.96 (31.97, 47.80) | 2.14 (0.25, 10.68) | <0.001 |
| LV V10 (%) | 23.79 (19.39, 28.39) | 0.00 (0.00, 0.01) | <0.001 |
| LV V20 (%) | 15.88 (11.27, 19.07) | 0.00 | -† |
| LV V30 (%) | 8.89 (5.25, 12.04) | 0.00 | -† |
| LV V40 (%) | 2.71 (1.02, 5.27) | 0.00 | -† |
| Right ventricle (RV) | |||
| RV Dmean (Gy) | 9.79 (7.46, 11.70) | 5.12 (4.12, 6.10) | <0.001 |
| RV Dmax (Gy) | 47.90 (43.20, 51.17) | 16.65 (13.56, 22.76) | <0.001 |
| RV V5 (%) | 52.70 (44.27, 62.12) | 39.36 (26.39, 46.32) | <0.001 |
| RV V10 (%) | 28.43 (18.77, 34.77) | 6.07 (1.18, 11.08) | <0.001 |
| RV V20 (%) | 14.88 (7.36, 20.91) | 0.00 (0.00, 0.15) | <0.001 |
| RV V30 (%) | 7.62 (2.29, 12.45) | 0.00 | -† |
| RV V40 (%) | 1.61 (0.10, 4.01) | 0.00 | -† |
| Left anterior descending artery (LAD) | |||
| LAD Dmean (Gy) | 39.38 (34.58, 43.89) | 3.11 (2.27, 4.70) | <0.001 |
| LAD Dmax (Gy) | 51.35 (49.09, 53.21) | 5.91 (4.30, 7.11) | <0.001 |
| LAD V5 (%) | 100.00 (97.73, 100.00) | 5.41 (0.00, 30.26) | <0.001 |
| LAD V10 (%) | 99.64 (86.31, 100.00) | 0.00 | -† |
| LAD V20 (%) | 95.27 (78.27, 100.00) | 0.00 | -† |
| LAD V30 (%) | 84.51 (68.69, 99.83) | 0.00 | -† |
| LAD V40 (%) | 59.53 (48.91, 75.84) | 0.00 | -† |
| Right coronary artery (RCA) | |||
| RCA Dmean (Gy) | 4.14 (3.20, 5.44) | 12.38 (9.17, 15.23) | <0.001 |
| RCA Dmax (Gy) | 5.61 (4.26, 8.30) | 18.68 (14.43, 24.42) | <0.001 |
| RCA V5 (%) | 17.95 (0.00, 66.71) | 100.00 (94.99, 100.00) | <0.001 |
| RCA V10 (%) | 0.00 | 67.06 (37.06, 97.45) | -† |
Data are presented as Median (25th percentile, 75th percentile). MHD, Mean Heart Dose. †P value not calculated because the statistical difference is self-evident due to absolute zero vs. positive range separation.