Table 3.
Dosimetric analysis of cardiac structures between the repolarization and rhythm groups in left-sided breast cancer patients with new-onset ECG abnormalities.
| Parameter | Repolarization abnormality (n=30) | Rhythm abnormality (n=14) | P value |
|---|---|---|---|
| Whole heart | |||
| MHD (Gy) | 7.96 (7.11, 9.99) | 7.09 (6.24, 7.98) | 0.02 |
| heart Dmax (Gy) | 52.97 (51.01, 55.35) | 50.58 (47.35, 52.59) | 0.02 |
| heart V5 (%) | 38.81 (31.56, 50.47) | 34.97 (28.03, 40.68) | 0.22 |
| heart V10 (%) | 20.41 (16.03, 26.66) | 15.55 (12.42, 20.79) | 0.03 |
| heart V20 (%) | 11.79 (9.13, 14.96) | 9.27 (6.23, 10.94) | 0.009 |
| heart V30 (%) | 7.13 (5.53, 8.40) | 4.31 (3.34, 6.12) | 0.001 |
| heart V40 (%) | 2.63 (1.46, 4.11) | 1.16 (0.48, 2.81) | 0.01 |
| Sinoatrial node (SAN) | |||
| SAN Dmean (Gy) | 3.09 (2.36, 4.38) | 3.32 (2.47, 4.42) | 0.64 |
| SAN Dmax (Gy) | 4.64 (3.66, 5.64) | 4.64 (3.63, 5.90) | 0.91 |
| SAN V5 (%) | 0.00 (0.00, 7.48) | 0.00 (0.00, 44.22) | 0.60 |
| Atrioventricular node (AVN) | |||
| AVN Dmean (Gy) | 3.20 (2.29, 4.38) | 2.69 (2.30, 3.79) | 0.51 |
| AVN Dmax (Gy) | 5.61 (2.94, 6.66) | 3.67 (3.29, 5.54) | 0.36 |
| AVN V5 (%) | 4.55 (0.00, 22.74) | 0.00 (0.00, 6.87) | 0.13 |
| Left ventricle (LV) | |||
| LV Dmean (Gy) | 10.10 (8.97, 11.01) | 7.97 (7.32, 9.02) | 0.003 |
| LV Dmax (Gy) | 51.23 (47.29, 53.22) | 48.37 (45.89, 51.64) | 0.12 |
| LV V5 (%) | 39.24 (34.87, 49.58) | 33.57 (29.16, 37.25) | 0.005 |
| LV V10 (%) | 26.19 (22.37, 30.19) | 19.32 (18.16, 26.12) | 0.003 |
| LV V20 (%) | 17.65 (14.03, 20.24) | 12.39 (9.17, 16.15) | 0.004 |
| LV V30 (%) | 10.05 (7.40, 12.33) | 6.48 (4.21, 8.83) | 0.004 |
| LV V40 (%) | 3.85 (1.15, 5.98) | 1.63 (0.73, 3.64) | 0.08 |
| Right ventricle (RV) | |||
| RV Dmax (Gy) | 49.07 (46.21, 51.78) | 44.1 (37.18, 49.71) | 0.03 |
| RV Dmean (Gy) | 10.98 (7.94, 13.15) | 8.45 (6.17, 11.10) | 0.05 |
| RV V5 (%) | 53.74 (47.04, 63.11) | 49.98 (37.76, 64.06) | 0.48 |
| RV V10 (%) | 30.09 (22.44, 38.76) | 21.67 (11.94, 34.51) | 0.08 |
| RV V20 (%) | 18.40 (9.42, 24.45) | 11.47 (3.01, 17.41) | 0.03 |
| RV V30 (%) | 9.52 (3.97, 13.58) | 5.23 (0.36, 7.86) | 0.01 |
| Left anterior descending artery (LAD) | |||
| LAD Dmax (Gy) | 51.61 (49.61, 54.18) | 50.99 (46.82, 52.54) | 0.23 |
| LAD Dmean (Gy) | 40.04 (37.71, 44.67) | 39.70 (32.22, 44.13) | 0.48 |
| LAD V5 (%) | 100.00 (100.00, 100.00) | 100.00 (96.87, 100.00) | 0.39 |
| LAD V10 (%) | 99.92 (87.21, 100.00) | 99.53 (82.80, 100.00) | 0.79 |
| LAD V20 (%) | 97.08 (82.97, 100.00) | 97.54 (74.02, 100.00) | 0.79 |
| LAD V30 (%) | 89.94 (72.23, 99.93) | 88.40 (66.46, 96.89) | 0.61 |
| LAD V40 (%) | 63.68 (58.32, 82.25) | 54.01 (48.03, 78.39) | 0.19 |
| Right coronary artery (RCA) | |||
| RCA Dmax (Gy) | 5.49 (4.19, 8.65) | 5.22 (4.20, 8.80) | 0.79 |
| RCA Dmean (Gy) | 3.74 (2.85, 5.45) | 3.93 (3.30, 5.45) | 0.88 |
| RCA V5 (%) | 14.15 (0.00, 58.65) | 1.27 (0.00, 67.80) | 0.49 |
Due to space limitations, some volumetric parameters for SAN, AVN, and RCA that showed no significant inter-group differences (P > 0.10) are omitted from the table. MHD, Mean Heart Dose.