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UHCVcon-57.3 cells expressing the entire HCV polyprotein 48 h after tetracycline withdrawal. (a) Low-power overview showing the alterations induced. w, membranous web; li, lipid droplets; cv, contiguous vesicles; drER, dilated rER forming vacuoles; N, nucleus. Bar, 1 μm. (b) Higher magnification of the membranous web (w), surrounded by clusters of contiguous vesicles (cv). Bar, 0.5 μm. (c) Vacuoles of dilated rER, carrying ribosomes on their surfaces. Bar, 0.5 μm.
