Table 4.

Quantitative outcomes- Harms/adverse events & BP changes.

Authors/Year	Harms/ Adverse events	P-value/CI	BP Change SBP/DBP (Metric)	P-value/CI
Rekha 2024 (30)	28 ADRs (71% recovered; 0 fatal)	N/A	N/A	N/A
Ho 2025 (34)	No diff Emergency Department visits/hospital visits/death	P > 0.55	N/A	N/A
Wang 2025a (26)	N/A	N/A	Controlled 13.5–16%; OR 2.87–3.58	P = 0.001
Sakane 2023 (28)	N/A	N/A	SBP- decreased by 3 mmHg/no DBP	P = 0.02 (not sig vs. ctrl)
Echeazarra 2021 (29)	N/A	N/A	'−0.34/−1.88 mmHg	P = 0.342/0.897
AlFraidan 2025 (27)	N/A	N/A	SBP and DBP decreased by 20mmHg & 14 mmHg respectively	P = 0.001 (ηÂ2 = 0.43/0.38)
Antia 2025 (25)	N/A	N/A	SBP and DBP decreased by 4 mmHg & 1 mmHg respectively	P = 0.22/0.40