Table 2.
Comparison of clinical outcomes between the oral glucose and placebo groups (N = 400)
| 50% Dextrose solution (n = 205) | Placebo solution (n = 195) | p* | |
|---|---|---|---|
| First BG level (mg/dL) | 37.0 [33.0, 39.0] | 37.0 [33.0, 39.0] | 0.47 |
| BG levels after the first treatment (mg/dL) | 68.0 [56.8, 77.3] | 60.0 [51.0, 74.0] | < 0.01* |
| < 40 | 7/205 (3.4) | 9/195 (4.6) | 0.73 |
| < 25 | 1/205 (0.5) | 1/195 (0.5) | 1.00 |
| Incremental BG level after the first treatment (mg/dL) | 30.0 [20.0, 42.0] | 23.0 [15.0, 36.0] | < 0.01* |
| Incremental BG level after any treatment† (mg/dL) | 28.0 [18.0,40.0] | 22.5 [14.0, 35.0] | < 0.01* |
| Number of solution doses needed | 1 [1, 1] | 1 [1, 1] | 0.39 |
| ≥ 2 | 23 (11.2) | 17 (8.9) | 0.48 |
| Intravenous dextrose therapy | 10 (4.9) | 17(8.7) | 0.18 |
| Hyperglycemia (> 180 mg/dL) | 0 [0, 0] | 0 [0, 0] | 1.00 |
| Duration of birth hospitalization (days) | 5 [4, 7] | 5 [4, 7] | 0.06 |
Data are presented in number (percentage) or median [25th,75th percentile]
†Two post-treatment BG measurements were not performed in the placebo group after the 2nd and 3rd doses
*p-value less than 0.05 is considered statistically significant
BG blood glucose