Table 3.
The association of OL clinical basic characteristics and 5-ALA-PDT therapeutic effect (n=31)
|
Basic clinical characteristics |
Therapeutic effect |
Chi-squared value |
p-value |
|||
|---|---|---|---|---|---|---|
|
Cases (n) |
Effective cases (n) |
Effective invalid cases rate (%) |
||||
|
*Expressed using corrected chi-squared; **expressed using Fisher’s exact probability method; & statistically significant, p<0.05. | ||||||
|
Gender |
Male |
18 |
3 |
85.7 |
- |
0.533** |
|
Female |
10 |
0 |
100 |
|||
|
Age in years |
<50 |
13 |
2 |
86.7 |
0.003 |
0.953* |
|
≥50 |
15 |
1 |
93.8 |
|||
|
Lesion location |
Ventral tongue |
17 |
0 |
100 |
10.473 |
0.003&** |
|
Floor of the mouth |
0 |
2 |
0 |
|||
|
Other |
11 |
1 |
91.7 |
|||
|
Pathological characteristics |
Simple hyperplasia |
22 |
1 |
95.7 |
4.147 |
0.156** |
|
Mild epithelial dysplasia |
4 |
2 |
66.7 |
|||
|
Moderate epithelial dysplasia |
2 |
0 |
100 |
|||
|
Lesion classification |
Homogeneous |
22 |
3 |
88 |
- |
1.000** |
|
Non-homogeneous |
6 |
0 |
100 |
|||
|
Smoking history |
Yes |
21 |
3 |
87.5 |
- |
1.000** |
|
No |
7 |
0 |
100 |
|||
|
Drinking history |
Yes |
20 |
3 |
87 |
- |
0.550** |
|
No |
8 |
0 |
100 |
|||
|
Chewing betel nut |
Yes |
8 |
1 |
88.9 |
- |
1.000** |
|
No |
20 |
2 |
90.9 |
|||
|
Lesion size |
<2 cm2 |
13 |
1 |
92.9 |
0 |
1.000* |
|
≥2 cm2 |
15 |
2 |
88.2 |
|||
|
Clinical symptoms (side effect) |
Yes |
28 |
1 |
96.6 |
- |
0.006&** |
|
No |
0 |
2 |
0 |
|||