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. 2026 Sep 29;24:955–964. doi: 10.3290/j.ohpd.c_2827

Table 3.

The association of OL clinical basic characteristics and 5-ALA-PDT therapeutic effect (n=31)

Basic clinical characteristics

Therapeutic effect

Chi-squared value

p-value

Cases (n)

Effective cases (n)

Effective invalid cases rate (%)

*Expressed using corrected chi-squared; **expressed using Fisher’s exact probability method; & statistically significant, p<0.05.

Gender

Male

18

3

85.7

-

0.533**

Female

10

0

100

Age in years

<50

13

2

86.7

0.003

0.953*

≥50

15

1

93.8

Lesion location

Ventral tongue

17

0

100

10.473

0.003&**

Floor of the mouth

0

2

0

Other

11

1

91.7

Pathological characteristics

Simple hyperplasia

22

1

95.7

4.147

0.156**

Mild epithelial dysplasia

4

2

66.7

Moderate epithelial dysplasia

2

0

100

Lesion classification

Homogeneous

22

3

88

-

1.000**

Non-homogeneous

6

0

100

Smoking history

Yes

21

3

87.5

-

1.000**

No

7

0

100

Drinking history

Yes

20

3

87

-

0.550**

No

8

0

100

Chewing betel nut

Yes

8

1

88.9

-

1.000**

No

20

2

90.9

Lesion size

<2 cm2

13

1

92.9

0

1.000*

≥2 cm2

15

2

88.2

Clinical symptoms

(side effect)

Yes

28

1

96.6

-

0.006&**

No

0

2

0