FIG. 6.

Amino acid sequence comparison of putative ECL2 of hASCT1, mASCT1, mASCT2, and hASCT2 indicates 27% sequence identity. Numbers at the left of the sequences correspond to the first and last amino acids shown. Common amino acids are shaded. Deletions in sequences are indicated by dashes. N-glycosylation sites are indicated by asterisks. Region C is hypervariable and contains N-linked oligosaccharides that negatively interfere with viral receptor function, whereas region B is highly conserved (see text).