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. 2026 Jul 1;23:92. doi: 10.1186/s12981-026-00913-1

Table 2.

Bivariate and multivariate logistic regression analysis of factors associated with MetS.

Covariates Bivariate O.R. (95% C.I., p-value) Multivariate O.R. (95% C.I., p-value)
Age ≥ 60 years 2.13 (0.89–5.12, p = 0.09) –
Menopause* 1.57 (0.60–4.65, p = 0.38) –
Physical activity ** 0.19 (0.04–0.59, p = 0.01) 0.10 (0.02–0.44, p = 0.005)
Arduous work*** 4.11 (1.65–11.33, p = 0.004) 6.58 (2.03–26.26, p = 0.003)
Active/former smoker 0.95 (0.40–2.22, p = 0.90) –
Alcohol abuse**** 1.08 (0.15–5.01, p = 0.93) –
Dyslipidemia (family history) 2.02 (0.86–4.92, p = 0.11) –
PWID 5.28 (0.83–41.78, p = 0.07) –
 ≥ 10 Years of HIV 2.00 (0.50–13.39, p = 0.38) –
 ≥ 10 Years of ART 2.81 (0.73–18.54, p = 0.19) –
CD4 nadir < 200 cells/mm3 1.77 (0.74–4.49, p = 0.21) –
 ≥ 5 Years of TAF use 1.17 (0.48–2.79, p = 0.72) –
 ≥ 10 Years of PI use 1.83 (0.72–4.52, p = 0.20) –
 ≥ 10 Years of INSTI use 1.20 (0.31–3.87, p = 0.77) –

* Defined as the absence of menstruation for more than 12 months, as reported by patients

** Engagement in any leisure-time physical exercise or activity performed at least once per week for a minimum duration of 60 consecutive minutes as reported by patients

***More than 1 standard drink per day (i.e., > 10–12 g of pure ethanol per day) as reported by patients

**** Farm laborer, domestic worker, factory laborer, healthcare assistant, nurse, factory worker, hotel/hospital cleaner

O.R.: Odds Ratio, C.I.: Confidence Interval, HIV: Human Immunodeficiency Virus, PWID: People Who Injected Drugs, AIDS: Acquired Immunodeficiency Syndrome, HBsAg: Hepatitis B Surface Antigen, HCVAb: Hepatitis C Virus Antibodies, ART: Antiretroviral Therapy, TAF: Tenofovir Alafenamide, PI: Protease Inhibitors, INSTI: Integrase Strand Transfer Inhibitors