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. 2026 Sep 28;13(6):e200653. doi: 10.1212/NXI.0000000000200653

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Multiple scatter plots showing correlations between serum and CSF biomarker concentrations. — Correlations between paired serum and CSF concentrations are shown for selected biomarkers, with serum concentration on the x-axis and CSF concentration on the y-axis (log scales). Time points are represented by color. Repeated measure correlation analysis between serum and CSF are shown in the lower right of each plot, with correlation coefficient (R) and p value. Of 31 biomarkers that were measured and detectable in both serum and CSF, only 7 were significantly correlated (p < 0.05).