FIG. 1.

(A) Schematic representation of the HSV-2 genome, showing the UL56 gene. The HSV genome is shown with its unique long (UL) and unique short (US) regions. The arrows indicate the open reading frames. (B) Amino acid sequence of the HSV-2 UL56 open reading frame. The arginine-rich region is underlined. The putative transmembrane domain is shown as a hatched box, and the surrounding basic residues are indicated (+). (C) Hydrophobicity plot of UL56 using the algorithm described by Kyte and Doolittle (27). The window size used is 21 amino acids. The predicted transmembrane domain is highlighted.