Official websites use .gov
A
.gov website belongs to an official
government organization in the United States.
Secure .gov websites use HTTPS
A lock (
) or https:// means you've safely
connected to the .gov website. Share sensitive
information only on official, secure websites.
Quality Allele Frequency (QAF) and Variant Allele Frequency (VAF) threshold and their ideal values are used for sites’ filtration in the genotype flow of mite pedigrees
| Genotype | VAF and QAF thresholds | Ideal value, interpretation |
|---|---|---|
| AA (Homozygous Reference) | <0.01 | ~0, Strong reference support |
| AB (Heterozygous) | 0.2–0.8 | ~0.5, Balanced allele representation |
| BB (Homozygous Alternate) | >0.9 | ~1, Strong alternate support |
VAF and QAF are both defined as unitless frequencies ranging from 0 to 1.
