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. 2026 Jun 15;26:1159. doi: 10.1186/s12885-026-16289-4

Table 2.

Therapeutic evaluation according to AML subtype with KIT mutation in TARGET

With AML1::ETO and KIT mutation Without AML1::ETO but with KIT mutation P value
Course 1
 Bone marrow 0.35
CR 78.6% (22/28) 90.6% (29/32)
Not CR 21.4% (6/28) 9.4% (3/32)
 MRD 0.05
Yes 30.0% (6/20) 4.0% (1/25)
No 70.0% (14/20) 96.0% (24/25)
Course 2
 Bone marrow 0.48
CR 96.4% (27/28) 100.0% (31/31)
Not CR 3.6% (1/28) 0.0% (0/31)
 MRD 0.44
Yes 5.0% (1/20) 0.0% (0/25)
No 95.0% (19/20) 100.0% (25/25)

P values were analyzed by the Chi-Square Test, compared with AML1::ETO and KIT mutation group

CR Complete remission, MRD Minimal residual disease