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. 2026 Jun 15;26:1159. doi: 10.1186/s12885-026-16289-4

Table 3.

Therapeutic evaluation according to KIT mutation with AML1::ETO in TARGET

AML1::ETO with KIT mutation AML1::ETO without KIT mutation P value
Course 1
 Bone marrow 0.81
CR 78.6% (22/28) 80.6% (79/98)
Not CR 21.4% (6/28) 19.4% (19/98)
 MRD 0.48
Yes 30.0% (6/20) 19.4% (14/72)
No 70.0% (14/20) 80.6% (58/72)
Course 2
 Bone marrow 0.95
CR 96.4% (27/28) 93.8% (91/97)
Not CR 3.6% (1/28) 6.2% (6/97)
 MRD 0.77
Yes 5.0% (1/20) 10.4% (7/67)
No 95.0% (19/20) 89.6% (60/67)

P values were analyzed by the Chi-Square Test, compared with AML1::ETO and KIT mutation group

CR Complete remission, MRD Minimal residual disease