Figure 4.

Competitive bone marrow engraftment of WT and NOD1×2−/− donor HSPCs both transplanted into same allogeneic host. (Panel A) Gating scheme for population numbers of WT (B6, CD45.1+, H-2Kb) and NOD1×2−/− (B6, CD41.2+, H-2Kb) donor cells in competitive allogeneic hematopoietic stem cell transplant 6 wk after transplant. (Panel B) Donor LSK+ cells in BALB/c recipient BM 6 wk after transplant. (C) Donor HSPC+ cells in BALB/c recipient BM 6 wk after transplant. n = 9 mice/gp. Error bars are SD, ***p < .001.