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. 2026 Sep 18;39:16959. doi: 10.3389/ti.2026.16959

TABLE 1.

GRADE-based recommendations used in this document, based on GRADE [15] and used in accordance with the European Society for Organ Transplantation methodology.

Target group Strong recommendation # (“we recommend”) Conditional recommendation
(“We suggest”)
Patients All or almost all informed people would follow the recommended advice for or against an intervention Most informed people would choose the recommended course of action, but a substantial number would not
Clinicians Most patients should receive the recommended course of action The health professional should acknowledge that different choices may be appropriate for individual patients and should devote time to the process of shared decision‐making by which they ensure that the informed choice reflects individual values and preferences
Policymakers The recommendation can be adopted as a health policy in most situations Policy making will require substantial debate and involvement of many stakeholders
#

Strong recommendations based on high-quality evidence will apply to most patients for whom these recommendations are made, but they may not apply to all patients in all conditions; no recommendation can take into account all of the unique features of individual patients and clinical circumstances.