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. 2026 Sep 18;39:16959. doi: 10.3389/ti.2026.16959
PICO question 2
In adult lung transplant recipients, should tacrolimus be used over cyclosporine to prevent the onset of CLAD?
Recommendation
• In adult lung transplant recipients, we recommend using tacrolimus over cyclosporine in the prevention of CLAD. (Strong recommendation in favor of the intervention, low certainty of evidence)