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. 2026 Sep 18;13:1900321. doi: 10.3389/fmed.2026.1900321

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© 2026 Zhou, Li, Wang, Kou and Wei.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Panel A shows a histological section with large, pale, well-defined villous structures, while panel B shows a section with irregular cellular proliferation and loss of normal villous architecture under pink and purple stains. — Histopathological findings confirming the diagnosis of twin tubal ectopic pregnancy. (A) Endometrial curettage specimen showing secretory-phase endometrium with stromal decidualization and focal Arias–Stella reaction (glandular nuclear atypia associated with ectopic pregnancy). No chorionic villi or trophoblastic cells are identified, excluding an intrauterine pregnancy (H&E, ×100). (B) Resected left fallopian tube specimen revealing two distinct foci of chorionic villi and trophoblastic cells, confirming twin ectopic gestation within the tubal lumen (H&E, ×100). The combined findings established the definitive diagnosis of unilateral twin tubal ectopic pregnancy.