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. 2026 Sep 18;14:1948171. doi: 10.3389/fpubh.2026.1948171

Table 2.

Annualized average percent change (AAPC) and annual percent change (APC) for tuberculosis subtypes in China from 1990 to 2023.

Disease Index ASIR ASPR ASMR ASDR
Years Change (%, 95CI) Years Change (%, 95CI) Years Change (%, 95CI) Years Change (%, 95CI)
TB AAPC 1990–2023 −3.833 (−3.995, −3.671) 1990–2023 −0.094 (−0.133, −0.054) 1990–2023 −8.183 (−8.482, −7.885) 1990–2023 −7.501 (−7.782, −7.221)
APC 1990–1994 −2.042 (−2.511, −1.571) 1990–2000 0.570 (0.524, 0.616) 1990–1992 −5.192 (−7.105, −3.239) 1990–1992 −4.783 (−9.936, 0.664)
APC 1994–2000 −3.802 (−4.151, −3.453) 2000–2004 −4.904 (−5.109, −4.698) 1992–1997 −8.396 (−9.228, −7.557) 1992–1997 −7.459 (−7.793, −7.125)
APC 2000–2004 −8.802 (−9.419, −8.181) 2004–2009 2.283 (2.126, 2.439) 1997–2003 −5.456 (−6.106, −4.803) 1997–2003 −6.134 (−6.502, −5.763)
APC 2004–2011 −2.435 (−2.715, −2.155) 2009–2023 −0.042 (−0.074, −0.010) 2003–2006 −13.734 (−15.475, −11.957) 2003–2006 −11.172 (−13.794, −8.470)
APC 2011–2019 −6.017 (−6.237, −5.797) 2006–2013 −10.481 (−10.968, −9.992) 2006–2013 −9.116 (−9.510, −8.720)
APC 2019–2023 1.221 (0.536, 1.910) 2013–2023 −7.038 (−7.332, −6.742) 2013–2023 −6.541 (−7.157, −5.922)
DS-TB AAPC 1990–2023 −3.877 (−3.967, −3.788) 1990–2023 −3.369 (−3.608, −3.130) 1990–2023 −8.332 (−8.602, −8.062) 1990–2023 −7.460 (−7.680, −7.240)
APC 1990–2000 −3.718 (−3.791, −3.645) 1990–2000 −2.551 (−2.783, −2.319) 1990–1997 −9.851 (−10.268, −9.433) 1990–1996 −9.130 (−9.538, −8.720)
APC 2000–2004 −8.492 (−8.816, −8.167) 2000–2004 −8.283 (−9.301, −7.253) 1997–2003 −5.238 (−5.916, −4.557) 1996–2002 −5.715 (−6.251, −5.176)
APC 2004–2010 −1.598 (−1.784, −1.411) 2004–2011 −0.562 (−1.030, −0.092) 2003–2006 −12.803 (−14.633, −10.934) 2002–2006 −10.234 (−11.185, −9.272)
APC 2010–2014 −4.399 (−4.737, −4.059) 2011–2019 −6.793 (−7.152, −6.434) 2006–2013 −9.228 (−9.741, −8.712) 2006–2019 −7.744 (−7.907, −7.581)
APC 2014–2019 −6.854 (−7.087, −6.620) 2019–2023 1.439 (0.313, 2.578) 2013–2023 −7.156 (−7.462, −6.849) 2019–2023 −3.876 (−4.895, −2.846)
APC 2019–2023 1.160 (0.803, 1.519)
MDR-TB AAPC 1990–2023 −2.859 (−3.487, −2.231) 1990–2023 −1.628 (−2.410, −0.846) 1990–2023 −6.714 (−7.265, −6.164) 1990–2023 −6.633 (−7.130, −6.135)
APC 1990–1991 69.311 (56.950, 82.644) 1990–1993 42.487 (36.868, 48.335) 1990–1992 41.037 (36.941, 45.255) 1990–1992 41.584 (36.960, 46.363)
APC 1991–1995 11.814 (9.166, 14.527) 1993–2000 −1.314 (−2.977, 0.378) 1992–1994 3.842 (−2.101, 10.145) 1992–1995 1.916 (−1.412, 5.356)
APC 1995–2000 −4.752 (−6.353, −3.124) 2000–2017 −10.294 (−10.693, −9.894) 1994–2003 −7.207 (−7.705, −6.707) 1995–2003 −7.855 (−8.520, −7.185)
APC 2000–2016 −11.580 (−11.836, −11.322) 2017–2023 0.503 (−1.635, 2.687) 2003–2009 −17.346 (−18.165, −16.519) 2003–2014 −17.550 (−17.919, −17.180)
APC 2016–2023 −0.270 (−1.275, 0.746) 2009–2013 −19.568 (−21.054, −18.056) 2014–2023 −5.767 (−6.336, −5.194)
APC 2013–2023 −6.411 (−6.840, −5.981)
XDR-TB AAPC 1990–2023 7.134 (5.766, 8.503) 1990–2023 7.800 (7.022, 8.578) 1990–2023 1.762 (0.778, 2.747) 1990–2023 41.657 (22.559, 60.755)
APC 1991–1995 54.847 (48.868, 61.067) 1991–1992 111.178 (96.130, 127.377) 1993–1995 76.087 (66.314, 86.433) 1991–1993 695.102 (476.266, 997.039)
APC 1995–2000 14.012 (9.609, 18.591) 1992–1998 29.191 (27.586, 30.814) 1995–2003 7.135 (5.808, 8.478) 1993–2001 14.461 (6.696, 22.791)
APC 2000–2006 −2.430 (−5.292, 0.518) 1998–2008 −0.625 (−1.195, −0.051) 2003–2008 −11.106 (−13.348, −8.807) 2001–2014 −11.650 (−14.582, −8.618)
APC 2006–2016 −7.004 (−8.270, −5.720) 2008–2015 −7.088 (−8.001, −6.166) 2008–2013 −15.037 (−17.180, −12.840) 2014–2023 −2.378 (−7.950, 3.531)
APC 2016–2023 3.353 (0.949, 5.814) 2015–2019 −1.617 (−3.890, 0.709) 2013–2023 −2.566 (−3.428, −1.696)
APC 2019–2023 6.399 (3.941, 8.915)
HIV-DS-TB AAPC 1990–2023 0.694 (0.426, 0.963) 1990–2023 2.062 (1.947, 2.177) 1990–2023 1.425 (0.793, 2.056) 1990–2023 1.768 (1.236, 2.299)
APC 1990–1998 7.209 (6.738, 7.682) 1990–1999 9.758 (9.618, 9.899) 1990–1993 17.091 (13.964, 20.304) 1990–1996 13.466 (12.297, 14.647)
APC 1998–2009 −1.788 (−2.107, −1.468) 1999–2009 −0.558 (−0.685, −0.430) 1993–2002 10.399 (9.540, 11.266) 1996–2002 9.734 (8.306, 11.180)
APC 2009–2013 0.447 (−1.074, 1.992) 2009–2015 0.192 (−0.086, 0.471) 2002–2013 −6.340 (−6.878, −5.797) 2002–2012 −5.215 (−5.785, −4.642)
APC 2013–2023 −1.687 (−2.056, −1.317) 2015–2019 −4.837 (−5.330, −4.341) 2013–2016 4.436 (0.061, 9.003) 2012–2016 1.411 (−1.043, 3.926)
2019–2023 0.239 (−1.151, 1.648) 2016–2023 −5.645 (−6.240, −5.047) 2016–2023 −4.843 (−5.299, −4.386)
HIV-MDR-TB AAPC 1990–2023 2.222 (1.283, 3.161) 1990–2023 4.323 (3.267, 5.379) 1990–2023 4.049 (2.830, 5.269) 1990–2023 4.081 (2.961, 5.201)
APC 1990–1992 77.932 (67.989, 88.463) 1990–1992 87.427 (76.026, 99.567) 1990–1994 59.036 (51.979, 66.421) 1990–1994 57.706 (51.239, 64.449)
APC 1992–1997 9.299 (6.524, 12.146) 1992–1999 12.043 (10.179, 13.938) 1994–2003 7.587 (5.612, 9.599) 1994–2003 7.983 (6.153, 9.845)
APC 1997–2002 0.015 (−2.524, 2.621) 1999–2003 −3.282 (−7.045, 0.634) 2003–2012 −15.343 (−16.898, −13.759) 2003–2012 −14.628 (−16.074, −13.155)
APC 2002–2014 −10.729 (−11.334, −10.120) 2003–2016 −8.207 (−8.809, −7.601) 2012–2023 −2.974 (−4.293, −1.637) 2012–2023 −3.305 (−4.518, −2.077)
APC 2014–2023 −0.040 (−1.084, 1.015) 2016–2023 0.476 (−1.195, 2.176)
HIV-XDR-TB AAPC 1990–2023 13.318 (11.537, 15.099) 1990–2023 16.308 (15.468, 17.148) 1990–2023 12.035 (10.127, 13.943) 1990–2023 67.028 (50.037, 84.019)
APC 1991–1997 64.165 (58.175, 70.380) 1991–1992 206.915 (187.801, 227.298) 1993–1996 95.316 (81.573, 110.097) 1991–1994 664.307 (520.031, 842.155)
APC 1997–2004 13.979 (9.821, 18.295) 1992–1998 44.315 (42.755, 45.893) 1996–2003 21.310 (17.627, 25.108) 1994–2002 29.355 (20.346, 39.037)
APC 2004–2012 −9.965 (−12.655, −7.190) 1998–2004 7.995 (6.828, 9.175) 2003–2012 −9.588 (−11.472, −7.663) 2002–2013 −8.038 (−12.050, −3.844)
APC 2012–2023 2.096 (0.200, 4.029) 2004–2015 −2.858 (−3.278, −2.436) 2012–2023 1.111 (−0.449, 2.696) 2013–2023 0.556 (−4.491, 5.871)
APC 2015–2019 2.118 (0.062, 4.215)
APC 2019–2023 6.010 (3.877, 8.188)