TABLE 2.
Comparison of deduced amino acid sequences of the P proteins of attenuated and wild-type MVs
Amino acid | Ed wt Pa | EdmBil P | CAM-70 P | Ne P | II-1 P | Gam P |
---|---|---|---|---|---|---|
29 | Ib | V | ||||
30 | E | Q | ||||
44 | G | R | ||||
46 | E | D | ||||
49 | T | A | A | |||
51 | R | K | K | T | ||
54 | K | E | ||||
56 | G | S | ||||
65 | L | F | ||||
79 | R | C | ||||
83 | P | S | S | S | ||
95 | I | T | ||||
97 | P | S | S | |||
98 | R | G | G | G | ||
99 | N | D | ||||
105 | T | A | ||||
109 | C | R | ||||
110 | Y | H | C | |||
111 | Y | H | ||||
121 | K | E | ||||
130 | M | V | ||||
138 | D | G | ||||
146 | N | D | ||||
165 | I | V | ||||
173 | I | T | ||||
195 | R | K | ||||
206 | L | P | ||||
207 | G | R | ||||
215 | P | L | ||||
217 | D | N | ||||
218 | P | L | ||||
219 | G | S | ||||
220 | R | M | ||||
225 | E | G | G | |||
228 | I | V | ||||
246 | L | S | ||||
259 | P | S | ||||
266 | G | A | D | |||
280 | A | V | ||||
285 | W | R | ||||
306 | Y | H | ||||
355 | R | K | ||||
377 | L | F | F | |||
390 | I | L | ||||
414 | V | I | ||||
419 | L | I | ||||
422 | M | I | ||||
447 | M | V | ||||
482 | M | L | ||||
492 | N | D | ||||
No. of changesb | 4 | 11 | 13 | 20 | 14 |
Single-letter amino acid code: bold letters denote nonconservative substitutions relative to the Edmonston wild-type (Ed wt) sequence.
Relative to Edmonston wild-type isolate.