TABLE 3.
Effect of preadsorbing with MBM cells on the titers of FIV-binding antibodies exhibited by vaccinated, mock-immunized, and control sera
| Cat group | Time of serum collection | ELISA antibody titera with: |
|||
|---|---|---|---|---|---|
| Whole FIV |
FIV gp |
||||
| Untreated | Adsorbed | Untreated | Adsorbed | ||
| FCPLB | Peakb | 5,200 | 1,600 | 4,800 | 3,000 |
| First challenge | 2,500 | 800 | 3,600 | 800 | |
| Second challengec | 1,200 | 600 | 1,200 | 600 | |
| ID-1 | Peak | 8,000 | 1,600 | 5,400 | 2,500 |
| First challenge | 4,400 | 1,600 | 4,200 | 1,800 | |
| Second challenge | 1,400 | 1,000 | 1,800 | 1,200 | |
| ID-2 | Peak | 4,200 | 1,000 | 5,200 | 1,800 |
| First challenge | 2,900 | 800 | 4,000 | 1,200 | |
| Second challenge | 1,400 | 800 | 1,600 | 800 | |
| ID-3 | Peak | 12,000 | 3,200 | 18,000 | 3,200 |
| First challenge | 6,200 | 1,800 | 12,000 | 2,200 | |
| Second challenge | 2,200 | 1,000 | 2,000 | 1,600 | |
| Mock-1 | Peak | 3,000 | <200 | 2,200 | <200 |
| First challenge | 1,400 | <200 | 1,400 | <200 | |
| Second challenge | 800 | <200 | 800 | <200 | |
| Mock-2 | Peak | 2,400 | <200 | 2,500 | <200 |
| First challenge | 2,000 | <200 | 2,000 | <200 | |
| Second challenge | 400 | <200 | 400 | <200 | |
| Infectedd | 12 mo post infection | 10,000 | 10,000 | 10,000 | 10,000 |
| Uninfected, unvaccinated | <200 | <200 | <200 | <200 | |
The experiment was performed twice with comparable results.
Peak, four months after initiation of immunization.
Second challenge, animals that had escaped infection after the first challenge alone.
Pool of sera 753, 1694, and 2508 described in Table 2.