TABLE 1.
Demographic, epidemiological, and clinical characteristics of four individuals chronically infected with HIV-1 with treatment failure undergoing structured treatment interruption
| Patient | Sexa | Age (yr) | Length (yr) of infectionb | Route of infectionc | Clinical statusd | Previous treatment (time on treatment) | Last treatment (duration) |
|---|---|---|---|---|---|---|---|
| 1 | M | 33 | 7 | IDU | C3 | SQV + RTV, 3TC, d4T (4 mo) | AZT, ddI, ABC (12 mo) |
| 2 | M | 33 | 6 | Sexual | C2 | AZT, ddC, ddI, 3TC, d4T, HU, IDV, NVP NFV, SQV + RTV (6 y) | 3TC, d4T, IDV + RTV (9 mo) |
| 3 | M | 32 | 8 | IDU | B3 | AZT, ddC, ddI, 3TC, d4T, HU, IDV, EFV, NFV, RTV, SQV (8 y) | ABC, d4T, EFV (12 mo) |
| 4 | F | 32 | 6 | Sexual | A1 | AZT, ddC (4 mo) | d4T, ddI, NVP (3 y) |
a
F, female; M, male.
b
Time elapsed since infection until STI.
c
IDU, intravenous drug use.
d
Clinical status according to the Centers for Disease Control and Prevention classification system (5a).