TABLE 2.
Lymphocyte and neutrophil infiltration into the CNS of recipients of CD4 T-cell-enriched splenocytes
| Donor cella type | No. of CD4 cells | No. of M133b cells | No. of Mac-1/ GR1 cells |
|---|---|---|---|
| B6 | (1.8 ± 0.3) × 105 | (3.3 ± 0.5) × 104 | (8.1 ± 2.4) × 104 |
| IFN-γ−/− | (2.6 ± 0.6) × 105 | (6.2 ± 1.4) × 104 | (9.3 ± 3.9) × 104 |
a
Each group consisted of three individual mice (six to nine per group) that received CD4 T-cell-enriched splenocytes from B6 or IFN-γ−/− mice.
b
Measured by intracellular staining for TNF-α. Values are shown after subtraction of background staining. The absolute number (± standard error) of virus-specific cells was calculated as described in the text.