Table 2.

Univariable analysis of factors associated with DAIR failure.

Categorical variables
	Failure $n/N$  (%)	No failure $n/N$  (%)	OR (95 % CI)	$p$  value
Male sex	$\mathrm{52}/\mathrm{91}$  (57.1)	$\mathrm{39}/\mathrm{91}$  (42.9)	0.80 (0.5–1.4)	0.438
Charlson Comorbidity Index $\ge$ 3	$\mathrm{18}/\mathrm{23}$  (78.3)	$\mathrm{5}/\mathrm{23}$  (21.7)	3.39 (1.2–9.5)	0.015
CRP $>$ 150 mg L−1	$\mathrm{32}/\mathrm{46}$  (69.6)	$\mathrm{14}/\mathrm{46}$  (30.4)	2.29 (1.1–4.6)	0.021
Bacteraemia	$\mathrm{12}/\mathrm{17}$  (70.6)	$\mathrm{5}/\mathrm{17}$  (29.4)	2.13 (0.7–6.3)	0.161
Fracture indication	$\mathrm{31}/\mathrm{60}$  (51.7)	$\mathrm{29}/\mathrm{60}$ (48.3)	0.88 (0.5–1.6)	0.669
Revision prosthesis	$\mathrm{51}/\mathrm{71}$  (71.8)	$\mathrm{20}/\mathrm{71}$  (28.2)	3.02 (1.6–5.5)	$<\mathrm{0.001}$
Cemented prosthesis	$\mathrm{75}/\mathrm{142}$  (52.8)	$\mathrm{67}/\mathrm{142}$  (47.2)	0.67 (0.3–1.3)	0.243
Hip PJI	$\mathrm{67}/\mathrm{117}$  (57.3)	$\mathrm{50}/\mathrm{117}$  (42.7)	1.34 (0.8–2.3)	0.277
Gram-negative infection	$\mathrm{28}/\mathrm{42}$  (66.7)	$\mathrm{14}/\mathrm{42}$  (33.3)	1.90 (0.9–3.9)	0.068
Polymicrobial infection	$\mathrm{17}/\mathrm{25}$  (68.0)	$\mathrm{8}/\mathrm{25}$  (32.0)	1.90 (0.8–4.7)	0.137
Continuous variables
	Failure median (IQR)	No failure median (IQR)	$p$  value
Age (years)	70 (63–79)	70 (65–77)	0.545
Charlson Comorbidity Index	1 (0–1)	1 (0–1)	0.098
Haemoglobin (g dL−1)	10.5 (9.4–11.6)	10.6 (9.5–11.6)	0.457
Leucocyte count (cell mm−3)	8250 (6420–11 570)	8780 (6503–12 615)	0.920
CRP (mg L−1)	77.5 (27–187)	61.5 (23–133)	0.023
Time from index arthroplasty to DAIR (days)	43 (27–208)	31 (20–39)	$<\mathrm{0.001}$

Denominators vary due to missing data and are shown where applicable. CRP: C-reactive protein; DAIR: debridement, antibiotics, and implant retention.