Table 3.

Multivariable analysis of factors associated with DAIR failure and derived clinical score.

Variable	$\mathit{\beta }$	Odds	95 % CI	$p$  value	Score
	coefficient	ratio
Revision prosthesis	0.970	2.64	1.20–5.81	0.017	3
Charlson Comorbidity Index $\ge$ 3	1.638	5.15	1.25–21.22	0.024	5
CRP $>$ 150 mg L−1	1.570	4.81	1.98–11.67	$<\mathrm{0.001}$	4
Time from index arthroplasty to DAIR, d−1	0.014	1.01	1.01–1.02	0.001	days/25 (0.04 d−1)
Gram-negative bacilli or polymicrobial infection	1.393	4.03	1.77–9.19	0.001	4

CCI $\ge$ 3 was present in 19/185 (10.3 %) patients included in the complete-case analysis (23/224 (10.3 %)) in the overall cohort). The final model included five predictors and 102 failure events. CRP: C-reactive protein; DAIR: debridement, antibiotics, and implant retention.