Skip to main content
. 2026 Aug 3;40(10):9041–9049. doi: 10.1007/s00464-026-13205-6

Table 2.

Factors associated with clinical reflux symptom control after peroral endoscopic myotomy

Variable Odds ratio 95% confidence interval P value
Age 1.05 1.01–1.09 0.011
Sex
 Female Ref Ref Ref
 Male 2.04 0.66–6.28 0.215
Preoperative BMI
 Underweight/normal weight (< 18.5–24.9 kg/m2) Ref Ref Ref
 Overweight (25.0–29.9 kg/m2) 0.99 0.18–5.30 0.987
 Obese (≥ 30 kg/m2) 0.52 0.11–2.43 0.405
Preoperative weight loss
  < 5 kg Ref Ref Ref
  > 5 kg 7.23 1.59–32.88 0.010
 Unknown 1.32 0.56–4.92 0.676
Preoperative symptom length
  < 1 year Ref Ref Ref
 1–3 years 1.59 0.40–6.25 0.509
  ≥ 4 years 0.73 0.18–2.96 0.663
 Unknown 1.64 0.19–14.01 0.652
Preoperative PPI use
 No Ref Ref Ref
 Yes 1.17 0.33–4.16 0.804
 Unknown 3.00 0.35–25.66 0.317
Preoperative GERD diagnosis
 No Ref Ref Ref
 Yes 0.74 0.20–2.75 0.655
Myotomy location
 Anterior Ref Ref Ref
 Posterior 1.89 0.25–14.34 0.539
 Unknown 0.15 0.01–2.52 0.189

BMI body mass index, PPI proton pump inhibitor, GERD gastroesophageal reflux disease