Table 2.
Factors associated with clinical reflux symptom control after peroral endoscopic myotomy
| Variable | Odds ratio | 95% confidence interval | P value |
|---|---|---|---|
| Age | 1.05 | 1.01–1.09 | 0.011 |
| Sex | |||
| Female | Ref | Ref | Ref |
| Male | 2.04 | 0.66–6.28 | 0.215 |
| Preoperative BMI | |||
| Underweight/normal weight (< 18.5–24.9 kg/m2) | Ref | Ref | Ref |
| Overweight (25.0–29.9 kg/m2) | 0.99 | 0.18–5.30 | 0.987 |
| Obese (≥ 30 kg/m2) | 0.52 | 0.11–2.43 | 0.405 |
| Preoperative weight loss | |||
| < 5 kg | Ref | Ref | Ref |
| > 5 kg | 7.23 | 1.59–32.88 | 0.010 |
| Unknown | 1.32 | 0.56–4.92 | 0.676 |
| Preoperative symptom length | |||
| < 1 year | Ref | Ref | Ref |
| 1–3 years | 1.59 | 0.40–6.25 | 0.509 |
| ≥ 4 years | 0.73 | 0.18–2.96 | 0.663 |
| Unknown | 1.64 | 0.19–14.01 | 0.652 |
| Preoperative PPI use | |||
| No | Ref | Ref | Ref |
| Yes | 1.17 | 0.33–4.16 | 0.804 |
| Unknown | 3.00 | 0.35–25.66 | 0.317 |
| Preoperative GERD diagnosis | |||
| No | Ref | Ref | Ref |
| Yes | 0.74 | 0.20–2.75 | 0.655 |
| Myotomy location | |||
| Anterior | Ref | Ref | Ref |
| Posterior | 1.89 | 0.25–14.34 | 0.539 |
| Unknown | 0.15 | 0.01–2.52 | 0.189 |
BMI body mass index, PPI proton pump inhibitor, GERD gastroesophageal reflux disease