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. 2026 Sep 2;18(9):e115690. doi: 10.7759/cureus.115690

Table 2. Injury characteristics, associated thoracic and non-thoracic injuries, and systemic analgesic use in patients receiving regional anaesthesia with systemic analgesia compared with those receiving systemic analgesia alone.

NSAIDs: Non-steroidal anti-inflammatory drugs; PCA: Patient-controlled analgesia; RA: Regional anaesthesia.

Note: Values are presented as n (%) or median (IQR), as appropriate. p-values represent between-group comparisons.

Characteristic Total (N=682) RA and systemic analgesia (n=126) Systemic analgesia only (n=556) p-value Statistical test, statistic, and effect size
Rib fractures
Number, median (IQR) 3 (2-4)* 4 (3-6) 3 (3-4) <0.001 Mann-Whitney U test
Laterality, n (%)
Unilateral 595 (87) 114 (90) 481 (87) 0.228 Pearson’s χ² test (overall); χ²(1)=1.451; Cramér’s V=0.046
Bilateral 87 (13) 12 (10) 75 (13)
Other thoracic injuries, n (%)
Lung contusion 103 (15) 33 (26) 70 (13) <0.001 Pearson’s χ² test; χ²(1)=14.819; Cramér’s V=0.147
Pneumothorax 153 (22) 54 (43) 99 (18) <0.001 Pearson’s χ² test; χ²(1)=37.046; Cramér’s V=0.233
Flail segment 30 (4) 14 (11) 16 (3) <0.001 Pearson’s χ² test; χ²(1)=16.559; Cramér’s V=0.156
Haemothorax 88 (13) 27 (21) 61 (11) 0.002 Pearson’s χ² test; χ²(1)=9.996; Cramér’s V=0.121
Subcutaneous emphysema 75 (11) 31 (25) 44 (8) <0.001 Pearson’s χ² test; χ²(1)=29.233; Cramér’s V=0.207
Injuries other than thoracic injuries, n (%) 283 (42) 55 (44) 228 (41) 0.587 Pearson’s χ² test; χ²(1)=0.296; Cramér’s V=0.021
Analgesia, n (%)
Paracetamol 634 (93) 121 (96) 513 (92) 0.136 Pearson’s χ² test; χ²(1)=2.226; Cramér’s V=0.057
NSAIDs 202 (30) 47 (37) 155 (28) 0.036 Pearson’s χ² test; χ²(1)=4.376; Cramér’s V=0.080
Opioids 593 (87) 121 (96) 472 (85) <0.001 Pearson’s χ² test; χ²(1)=11.234; Cramér’s V=0.128
PCA 358 (52) 104 (83) 254 (46) <0.001 Pearson’s χ² test; χ²(1)=55.953; Cramér’s V=0.286