Table 4.

Distribution of resistance-associated genes in XDR and non-XDR isolates.

Gene category	Gene	XDR-positive (n=24), n (%)	Non-XDR-positive (n=56), n (%)	OR (95% CI)	Unadjusted P	q value (BH-FDR)
Antimicrobial resistance-associated	blaKPC	4 (16.70)	4 (7.10)	2.60 (0.59–11.41)	0.232	0.723
Antimicrobial resistance-associated	blaNDM	2 (8.30)	3 (5.40)	1.61 (0.25–10.29)	0.633	0.723
Antimicrobial resistance-associated	oprD amplification failure	18 (75.00)	37 (66.10)	1.54 (0.51–4.67)	0.599	0.723
Antimicrobial resistance-associated	blaVIM	2 (8.30)	2 (3.60)	2.45 (0.33–18.54)	0.579	0.723
Disinfectant resistance	merA	5 (20.80)	8 (14.30)	1.58 (0.46–5.44)	0.516	0.723
Disinfectant resistance	qacEΔ1-sul1	14 (58.30)	15 (26.80)	3.83 (1.40–10.45)	0.011	0.088
Disinfectant resistance	tehA	2 (8.30)	4 (7.10)	1.18 (0.20–6.93)	1.000	1.000
Disinfectant resistance	oqxA	1 (4.20)	1 (1.80)	2.39 (0.14–39.89)	0.513	0.723

All P values were calculated using two-sided Fisher’s exact test. q values were calculated by the Benjamini–Hochberg false discovery rate procedure across the eight comparisons in this exploratory family; no association retained significance after correction (all q > 0.05). Holm-adjusted P for qacEΔ1-sul1 was 0.088. OR, odds ratio; CI, confidence interval; BH-FDR, Benjamini–Hochberg false discovery rate. “oprD amplification failure” denotes failure to amplify the expected PCR target and does not imply gene deletion or loss of protein expression.