Table 2. Substituent patterns and α-amylase inhibitory activity (IC50) of additional oxadiazole–sulfonamide hybrids 11d–g derived from the scaffold previously discussed in the antimicrobial activity section.
| Compound | Substituent (R) | α-Amylase IC50 (µM) |
|---|---|---|
| 11d | Indole | 2.34 |
| 11e | Indoline | 6.23 |
| 11f | 6-Nitro indoline | 6.59 |
| 11g | 1-Benzhydryl piperazine | 7.15 |